If you have the urge to be wasteful, here’s something fun you can do that may help.

Start Visual Studio’s “Create GUID” utility (Tools|Create GUID) and click New Guid a few hundred times.

As you wantonly create hordes of GUIDs that, unloved, instantly disappear into the ether, never to be seen again, you should take the opportunity to reflect on this task, being one of life’s more fruitless activities, and soon you will be feeling much better.

If this still doesn’t help, write a little program that calls CoCreateGuid, hundreds, millions, or even billions of times. You can even let the program run by itself, unmonitored and unchecked, gleefully consuming this precious resource, while you read War and Peace in its entirety. If that doesn’t fix it for you, nothing will.